Biochemical pathway evaluation

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Cellular Toxicity (ATP assay)
ATP monitoring can be used to assess the cytotoxic, cytostatic and proliferative effects of pharmaceutical, chemical and environmental compounds, and nutrients. ATP is a marker for cell viability because it is present in all metabolically active cells and the concentration declines very rapidly when the cells undergo necrosis or apoptosis. The ATP test system is luminescent assay based on the production of light caused by the reaction of ATP with added luciferase and D-luciferin. The emitted light is proportional to the ATP concentration.