Ex vivo experiments

Home >

Organ Bath experiment
Ex vivo assay useful to characterize the agonist or antagonist activity profile of ligands towards receptors present in different organs (ileum, vas deferens, bladder) at pre-junctional or post-junctional level. This method can be performed studying the interference of tested compounds on electrically-evoked contractions (pre-junctional study) or on stimulation induced by esogen ligands such as charbachol, Noradrenaline or substance P (post-junctional study).